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生命のしなやかさを支える膜臨界場の実像を、力学的な側面から明らかにすることを目指します。

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氏原 嘉洋
Yoshihiro Ujihara
名古屋工業大学大
学院工学研究科 工学専攻 准教授

主な発表論文

  1. Y. Ogura, H. Ito, S. Sugita, M. Nakamura, Y. Ujihara*. Decrease in Ca2+ concentration in quail cardiomyocytes is faster than that in rat cardiomyocytes. Processes, 10: 508 (2022) 

  2. K. Hashimoto*, A. Kodama, M. Ohira, M. Kimoto, R. Nakagawa, Y. Usui, Y. Ujihara, A. Hanashima, S. Mohri. Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15, iScience, 25: 104337 (2022).

  3. Y. Ujihara, M. Kanagawa, S. Mohri, S. Takatsu, K. Kobayashi, K. Naruse, Y. Katanosaka*. Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure. Nat Commun, 10: 5754 (2019) 

  4. Y. Ujihara, K. Iwasaki, S. Takatsu, K. Hashimoto, K. Naruse, S. Mohri, Y. Katanosaka*. Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodeling. Cardiovasc Res, 111:348-61 (2016)  

  5. Y. Katanosaka*, K. Iwasaki, Y. Ujihara, S. Takatsu, K. Nishitsuji, M. Kanagawa, A. Sudo, T. Toda, K. Katanosaka, S. Mohri, K. Naruse. TRPV2 is critical for cardiac function and compensatory hypertrophic response to hemodynamic stress. Nat Commun, 5: 3932 (2014)  

氏原班

膜臨界場の力学的定量化と特殊膜構造に依存したしなやかさの評価

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